The comprehension of the role and use of text cohesion and coherence markers in medication leaflets by pharmacy students is crucial for understanding the overall meaning and structure of a medication leaflet. The comprehension of these markers is tested by using the re-order the paragraphs exercises. The study results point that coping with understanding the role of these markers is directly connected to the students’ overall level of language knowledge and skills. A higher level of English language knowledge and skills helps to increase students’ understanding of the role of the text cohesion markers. Understanding the gist of a text and its general purpose as well as knowledge of the well-established structure of a professional text help students tackle text coherence. The study gives an insight into when and how to teach text markers in an ESP course for pharmacy students.